Optoepigenetics: An acetylation photoswitch

March 14th, 2016 by Andreas S Madsen

Nature Chemical Biology 12, 306 (2016). doi:10.1038/nchembio.2049

Authors: Andreas S Madsen & Christian A Olsen

Histone 3 lysine 9 acetylation (H3K9ac) levels were modulated by photoresponsive histone deacetylase (HDAC) inhibitors to perturb the transcription of genes involved in cell cycle regulation and mitochondrial function.