An excreted small molecule promotes <i>C. elegans</i> reproductive development and aging
July 18th, 2019 by Andreas H. Ludewig
Nature Chemical Biology, Published online: 18 July 2019; doi:10.1038/s41589-019-0321-7
Male C. elegans excrete an N-acylated glutamine that acts via evolutionarily conserved nuclear hormone receptor and chemosensory pathways to counteract dauer diapause and accelerate sexual maturation of hermaphrodites, at the cost of shortening hermaphrodite lifespan.