Engineering peptide ligase specificity by proteomic identification of ligation sites
November 20th, 2017 by Amy M Weeks
Engineering peptide ligase specificity by proteomic identification of ligation sites
Engineering peptide ligase specificity by proteomic identification of ligation sites, Published online: 20 November 2017; doi:10.1038/nchembio.2521
A comprehensive characterization of peptide ligase specificity using proteome-derived peptide libraries enables the identification of 72 new subtiligases and their application to site-specific bioconjugation and sequencing of the cellular N terminome.