RNA folding: A clear path to RNA catalysis

November 17th, 2015 by Amanda Solem

Nature Chemical Biology 11, 906 (2015). doi:10.1038/nchembio.1954

Authors: Amanda Solem & Alain Laederach

A new high-resolution crystal structure of the subdomain from a catalytically active group II intron reveals important conformational rearrangements necessary to achieve the fully formed catalyst. This structure provides the first atomic-resolution structure of an RNA folding intermediate.