Host-pathogen interactions: A cholera surveillance system

February 22nd, 2016 by Aaron T Wright

Nature Chemical Biology 12, 203 (2016). doi:10.1038/nchembio.2039

Author: Aaron T Wright

Bacterial pathogen–secreted proteases may have a key role in inhibiting a potentially widespread host-pathogen interaction. Activity-based protein profiling enabled the identification of a major Vibrio cholerae serine protease that limits the ability of a host-derived intestinal lectin to bind to the bacterial pathogen in vivo.